Quantitative sensory testing of persistent pain after video-assisted thoracic surgery lobectomy

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Standard

Quantitative sensory testing of persistent pain after video-assisted thoracic surgery lobectomy. / Wildgaard, Kim; Ringsted , TK; Hansen, HJ; Petersen, RH; Kehlet, Henrik.

I: British Journal of Anaesthesia, Bind 108, 2011, s. 126-33.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Wildgaard, K, Ringsted , TK, Hansen, HJ, Petersen, RH & Kehlet, H 2011, 'Quantitative sensory testing of persistent pain after video-assisted thoracic surgery lobectomy', British Journal of Anaesthesia, bind 108, s. 126-33. https://doi.org/10.1093/bja/aer325

APA

Wildgaard, K., Ringsted , TK., Hansen, HJ., Petersen, RH., & Kehlet, H. (2011). Quantitative sensory testing of persistent pain after video-assisted thoracic surgery lobectomy. British Journal of Anaesthesia, 108, 126-33. https://doi.org/10.1093/bja/aer325

Vancouver

Wildgaard K, Ringsted TK, Hansen HJ, Petersen RH, Kehlet H. Quantitative sensory testing of persistent pain after video-assisted thoracic surgery lobectomy. British Journal of Anaesthesia. 2011; 108:126-33. https://doi.org/10.1093/bja/aer325

Author

Wildgaard, Kim ; Ringsted , TK ; Hansen, HJ ; Petersen, RH ; Kehlet, Henrik. / Quantitative sensory testing of persistent pain after video-assisted thoracic surgery lobectomy. I: British Journal of Anaesthesia. 2011 ; Bind 108. s. 126-33.

Bibtex

@article{354989b9f39b4919959f8ae318e7aaa3,
title = "Quantitative sensory testing of persistent pain after video-assisted thoracic surgery lobectomy",
abstract = "Background Video-assisted thoracic surgery (VATS) lobectomy may potentially reduce the risk of post-thoracotomy pain syndrome (PTPS). However, it may still carry a risk of intraoperative nerve damage and thereby development of PTPS. Thus, our aim was to present a detailed long-term neurophysiological characterization of PTPS after VATS.Methods Quantitative sensory testing, using thermal and mechanical stimuli, was performed in 13 PTPS patients and 35 pain-free patients recruited 33 months after VATS lobectomy.Results When comparing the operated side with the control side in PTPS patients, increased thresholds of tactile and warmth detection were observed, while in pain-free patients, increased thresholds of warmth detection, cool detection, and heat pain were demonstrated. At the anterior porthole, pain-free patients displayed increased threshold to thermal detection when compared with the control side. Only side-to-side difference for tactile detection threshold was increased in PTPS patients compared with pain-free patients. Assessment of central sensitization showed no significant differences within or between PTPS and pain-free patients nor did group comparison of area of hypo- and hyperaesthesia to cool. Anxiety and depression scores (HADS) were higher in PTPS patients, but the area of hyper- and hypoaesthesia did not differ significantly between HADS groups.Conclusions Increased sensory thresholds suggest nerve injury to be present on the operated side in both PTPS and pain-free patients. However, no significant quantitative differences between PTPS and pain-free patients could be found, implicating the presence of factors other than intercostal nerve injury as important for development of PTPS after VATS lobectomy.",
keywords = "Faculty of Health and Medical Sciences, Intercostal Nerves, neuralgia, pain, postoperative, pulmonary surgical procedures, thoracic surgery, video assisted",
author = "Kim Wildgaard and TK Ringsted and HJ Hansen and RH Petersen and Henrik Kehlet",
year = "2011",
doi = "10.1093/bja/aer325",
language = "English",
volume = " 108",
pages = "126--33",
journal = "British Journal of Anaesthesia",
issn = "0007-0912",
publisher = "Oxford University Press",

}

RIS

TY - JOUR

T1 - Quantitative sensory testing of persistent pain after video-assisted thoracic surgery lobectomy

AU - Wildgaard, Kim

AU - Ringsted , TK

AU - Hansen, HJ

AU - Petersen, RH

AU - Kehlet, Henrik

PY - 2011

Y1 - 2011

N2 - Background Video-assisted thoracic surgery (VATS) lobectomy may potentially reduce the risk of post-thoracotomy pain syndrome (PTPS). However, it may still carry a risk of intraoperative nerve damage and thereby development of PTPS. Thus, our aim was to present a detailed long-term neurophysiological characterization of PTPS after VATS.Methods Quantitative sensory testing, using thermal and mechanical stimuli, was performed in 13 PTPS patients and 35 pain-free patients recruited 33 months after VATS lobectomy.Results When comparing the operated side with the control side in PTPS patients, increased thresholds of tactile and warmth detection were observed, while in pain-free patients, increased thresholds of warmth detection, cool detection, and heat pain were demonstrated. At the anterior porthole, pain-free patients displayed increased threshold to thermal detection when compared with the control side. Only side-to-side difference for tactile detection threshold was increased in PTPS patients compared with pain-free patients. Assessment of central sensitization showed no significant differences within or between PTPS and pain-free patients nor did group comparison of area of hypo- and hyperaesthesia to cool. Anxiety and depression scores (HADS) were higher in PTPS patients, but the area of hyper- and hypoaesthesia did not differ significantly between HADS groups.Conclusions Increased sensory thresholds suggest nerve injury to be present on the operated side in both PTPS and pain-free patients. However, no significant quantitative differences between PTPS and pain-free patients could be found, implicating the presence of factors other than intercostal nerve injury as important for development of PTPS after VATS lobectomy.

AB - Background Video-assisted thoracic surgery (VATS) lobectomy may potentially reduce the risk of post-thoracotomy pain syndrome (PTPS). However, it may still carry a risk of intraoperative nerve damage and thereby development of PTPS. Thus, our aim was to present a detailed long-term neurophysiological characterization of PTPS after VATS.Methods Quantitative sensory testing, using thermal and mechanical stimuli, was performed in 13 PTPS patients and 35 pain-free patients recruited 33 months after VATS lobectomy.Results When comparing the operated side with the control side in PTPS patients, increased thresholds of tactile and warmth detection were observed, while in pain-free patients, increased thresholds of warmth detection, cool detection, and heat pain were demonstrated. At the anterior porthole, pain-free patients displayed increased threshold to thermal detection when compared with the control side. Only side-to-side difference for tactile detection threshold was increased in PTPS patients compared with pain-free patients. Assessment of central sensitization showed no significant differences within or between PTPS and pain-free patients nor did group comparison of area of hypo- and hyperaesthesia to cool. Anxiety and depression scores (HADS) were higher in PTPS patients, but the area of hyper- and hypoaesthesia did not differ significantly between HADS groups.Conclusions Increased sensory thresholds suggest nerve injury to be present on the operated side in both PTPS and pain-free patients. However, no significant quantitative differences between PTPS and pain-free patients could be found, implicating the presence of factors other than intercostal nerve injury as important for development of PTPS after VATS lobectomy.

KW - Faculty of Health and Medical Sciences

KW - Intercostal Nerves

KW - neuralgia

KW - pain, postoperative

KW - pulmonary surgical procedures

KW - thoracic surgery, video assisted

U2 - 10.1093/bja/aer325

DO - 10.1093/bja/aer325

M3 - Journal article

VL - 108

SP - 126

EP - 133

JO - British Journal of Anaesthesia

JF - British Journal of Anaesthesia

SN - 0007-0912

ER -

ID: 49813930