Research areas

  1. Published

    Prediction of the receptor conformation for iGluR2 agonist binding: QM/MM docking to an extensive conformational ensemble generated using normal mode analysis

    Sander, T., Liljefors, T. & Balle, T., 2008, In: Journal of Molecular Graphics and Modelling. 26, 8, p. 1259-1268

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Dipeptide derivatives of AZT: Synthesis, chemical stability, activation in human plasma, hPEPT1 affinity, and antiviral activity

    Santos, C., Morais, J., Gouveia, L., de Clercq, E., Pannecouque, C., Nielsen, C. U., Steffansen, B., Moreira, R. & Gomes, P., 2008, In: ChemMedChem. 3, 6, p. 970-978

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Chemometric methods applied to herbal medicinal products: St. Johns wort

    Schmidt, B., 2008, København: Det Farmaceutiske Fakultet. 190 p.

    Research output: Book/ReportPh.D. thesisResearch

  4. Published

    GABA Neurotransmission: An overview

    Schousboe, Arne & Waagepetersen, Helle S., 2008, Handbook of Neurochemistry and Molecular Neurobiology: Neurotransmitter Systems. Vizi, E. S. (ed.). The Netherlands: Springer Publishing Company, p. 213-226

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  5. Published

    Dimeric Building Blocks for Solid-Phase Synthesis of α-Peptide-β-Peptoid Chimeras

    Seigan, G. B., Vedel, L., Matthias, W., Jaroszewski, J. W., Olsen, Christian Adam & Franzyk, Henrik, 2008, In: Synthesis. 2008, 15, p. 2381-2390 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Library of biphenyl privileged substructures using a safety-catch linker approach

    Severinsen, R., Bourne, G. T., Tran, T. T., Ankersen, M., Begtrup, M. & Smythe, M. L., 2008, In: Journal of Combinatorial Chemistry. 10, 4, p. 557-566

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Metabolic activation of carboxylic acids

    Skonberg, C., Olsen, J., Madsen, K. G., Hansen, S. H. & Grillo, M. P., 2008, In: Expert Opinion on Drug Metabolism & Toxicology. 4, 4, p. 425-438

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Towards on-site pathogen detection using antibody-based sensors

    Skottrup, P. D., Nicolaisen, M. & Justesen, A. F., 2008, In: Biosensors and Bioelectronics. 24, 3, p. 339-348 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Carroll rearrangement to construct the norneolignan skeleton

    Skytte, D. M., Rasmussen, H. B. & Christensen, Søren Brøgger, 2008, In: Natural Product Research. 22, 2, p. 116-123

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Inhibition of the betaine-GABA transporter (mGAT2/BGT-1) modulates spontaneous electrographic bursting in the medial entorhinal cortex (mEC)

    Smith, M. D., Saunders, G. W., Clausen, Rasmus Prætorius, Frølund, Bente, Krogsgaard-Larsen, Povl, Larsson, O. M., Schousboe, Arne, Wilcox, K. S. & White, H. S., 2008, In: Epilepsy Research. 79, 1, p. 6-13

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Flexible dosing of tincture of opium in the management of opioid withdrawal: pharmacokinetics and pharmacodynamics

    Somogyi, A. A., Larsen, M., Abadi, R. M., Jittiwutikarn, J., Ali, R. & White, J. M., 2008, In: British Journal of Clinical Pharmacology. 66, 5, p. 640-647

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Combining HPLC-PDA-MS-SPE-NMR with circular dichroism for complete natural product characterization in crude extracts: Levorotatory gossypol in Thespesia danis

    Sprogøe, K., Stærk, Dan, Ziegler, H. L., Jensen, T. H., Holm-Møller, S. B. & Jaroszewski, J. W., 2008, In: Journal of Natural Products. 71, 4, p. 516-519

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    HPLC-SPE-NMR in natural products research

    Sprogøe, K., 2008, København: Det Farmaceutiske Fakultet. 128 p.

    Research output: Book/ReportPh.D. thesisResearch

  14. Published

    Pharmacokinetic-Pharmacodynamic modeling of morphine and oxycodone concentrations and analgesic effect in a multimodal experimental pain model

    Staahl, C., Upton, R., Foster, D. J. R., Christrup, Lona Louring, Kristensen, K., Hansen, S. H., Arendt-Nielsen, L. & Drewes, A. M., 2008, In: Journal of Clinical Pharmacology. 48, 5, p. 619-631

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Mild psychoactive constituents of Mentha aquatica L.

    Stafford, G. I., Almqvist, J. P., Vangsøe, S. A. K., Olsen, H. T., Christensen, Søren Brøgger, Adsersen, A., Jäger, A. K. & van Staden, J., 2008, In: South African Journal of Botany. 2, p. 389

    Research output: Contribution to journalConference abstract in journalResearch

  16. Published

    Review on plants with CNS-effects used in traditional South African medicine against mental diseases

    Stafford, G. I., Pedersen, M. E., van Staden, J. & Jäger, A. K., 2008, In: Journal of Ethnopharmacology. 119, 3, p. 513-37

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Fra Sims til Biosims: et computerspil om lægemiddelstoffers biotilgængelighed

    Steffansen, B. & Gram, L. K., 2008, In: Lægemiddelforskning. p. 19-21

    Research output: Contribution to journalJournal articleCommunication

  18. Published

    Novel wound models for characterizing ibuprofen release from foam dressings

    Steffansen, B. & Herping, S. P. K., 2008, In: Internation Journal of Pharmaceutics. 364, 1, p. 150-155

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Giftstoffer fra hvepse og edderkopper i forskning og lægemiddeludvikling

    Strømgaard, Kristian, 2008, In: Carlsbergfondet. Aarsskrift. p. 42-47

    Research output: Contribution to journalJournal articleCommunication

  20. Published

    Application of enriched stable isotopes as tracers in biological systems: a critical review

    Stürup, Stefan, Hansen, H. R. & Gammelgaard, Bente, 2008, In: Analytical and Bioanalytical Chemistry. 390, 2, p. 541-554

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    Cloning of the pig PEPT2 (pPEPT2) and characterization of the effects of epidermal growth factor (EGF) on pPEPT2-mediated peptide uptake in the renal porcine cell line LLC-PK1

    Søndergaard, H. B., Bravo, S. A., Nielsen, C. U., Frøkjær, Sven & Larsen, Birger Brodin, 2008, In: European Journal of Pharmaceutical Sciences. 33, 4-5, p. 332-342

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    hPEPT1 is responsible for uptake and transport of Gly-Sar in the human bronchial airway epithelial cell-line Calu-3

    Søndergaard, H. B., Larsen, Birger Brodin & Nielsen, C. U., 2008, In: Pflügers Archiv: European Journal of Physiology. 456, 3, p. 611-622

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Using an action research process in pharmacy practice research: A cooperative project between university and internship pharmacies

    Sørensen, E. W. & Nørgaard, Lotte Stig, 2008, In: Research in Social and Administrative Pharmacy. 4, 4, p. 384-401

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Risiko for hjerteflimmer afsløres med computermodel

    Taboureau, O., Brunak, S. & Jørgensen, Flemming Steen, 2008, In: Lægemiddelforskning. p. 31-33

    Research output: Contribution to journalJournal articleCommunication

  25. Published

    Involvement of organic anion transporting polypeptide 1a5 (Oatp1a5) in intestinal absorption of endothelin receptor antagonist in rats

    Tani, T., Gram, L. K., Arakawa, H., Kikuchi, A., Chiba, M., Ishii, Y., Steffansen, B. & Tamai, I., 2008, In: Pharmaceutical Research. 25, 5, p. 1085-1091 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Studies on human insulin adsorption kinetics at an organic-aqueous interface determined using a label-free electroanalytical approach

    Thomsen, A. E., Jensen, H., Jørgensen, Lene, van de Weert, Marco & Østergaard, Jesper, 2008, In: Colloids and Surfaces B: Biointerfaces. 63, 2, p. 243-248

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Characterization and physical stability of spray dried solid dispersions of probucol and PVP-K30

    Thybo, P., Pedersen, B. L., Hovgaard, L., Holm, R. & Mullertz, Anette , 2008, In: Pharmaceutical Development and Technology. 13, 5, p. 375-86 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Droplet size measurements for spray dryer scale-up

    Thybo, P., Hovgaard, L., Andersen, S. K. & Lindeløv, J. S., 2008, In: Pharmaceutical Development and Technology. 13, 2, p. 93-104

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Scaling up the spray drying process from pilot to production scale using an atomized droplet size criterion

    Thybo, P., Hovgaard, L., Lindeløv, J. S., Brask, A. & Andersen, S. K., 2008, In: Pharmaceutical Research. 25, 7, p. 1610-1620

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Regulation of GABAB receptors by extracellular proteins and phosphorylation

    Tiao, J. Y., Bradaia, A., Jensen, A. A., Biermann, B., Bräuner, Hans, Müller, M., Kaupmann, K., Gassmann, M. & Bettler, B., 2008, In: Neuropharmacology. 4, p. 626

    Research output: Contribution to journalConference abstract in journalResearch

  31. Published

    Cryopreservation of differentiated HL-60 cells for pyrogen testing

    Timm, M., Bartelt, S., Moesby, L. & Hansen, E. W., 2008, In: Journal of Immunological Methods. 339, 2, p. 146-152

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Immunomodulatory effects of honey cannot be distinguished from endotoxin

    Timm, M., Bartelt, S. & Hansen, E. W., 2008, In: Cytokine. 42, 1, p. 113-20

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Nedfrysning af immunceller kan overflødiggøre forsøgskaniner i lægemiddelkontrol

    Timm, M., Moesby, L. & Hansen, E. W., 2008, In: Lægemiddelforskning. p. 43-45

    Research output: Contribution to journalJournal articleCommunication

  34. Published

    High-throughput small angle X-ray scattering from proteins in solution using a microfluidic front-end

    Toft, K. N., Vestergaard, Bente, Nielsen, S. S., Snakenborg, D., Jeppesen, Mads Gravers, Jacobsen, J. K., Arleth, Lise & Kutter, J. P., 2008, In: Analytical Chemistry. 80, 10, p. 3648-3654 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Small angle X-ray scattering study of calreticulin reveals conformational plasticity

    Toft, K. N., Larsen, N., Jørgensen, Flemming Steen, Højrup, P., Houen, G. & Vestergaard, Bente, 2008, In: BBA General Subjects. 1784, 9, p. 1265-1270

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    A new oxygenated ursane derivative from Canthium multiflorum

    Traore, M., Jaroszewski, J. W., Olsen, C. E., Ouédraogo, J. B., Pierre, G. I., Nacoulma, O. G., Guiguemdé, T. R. & Christensen, Søren Brøgger, 2008, In: Planta Medica. 74, 5, p. 560-562 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Phytochemical studies of plants used as antimalarials in Burkina Faso

    Traore, M., 2008, København: Det Farmaceutiske Fakultet. 160 p.

    Research output: Book/ReportPh.D. thesisResearch

  38. Published

    'I'm happy if I can help': public views on future medicines and gene-based therapy in Iceland

    Traulsen, Janine Marie, Björnsdóttir, I. & Almarsdóttir, A. B., 2008, In: Community Genetics. 11, 1, p. 2-10

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Immunogenicity of biopharmaceuticals: methods to reduce immunogenicity and biosimilars

    van de Weert, Marco & Møller, E. H., 2008, Immunogenicity of biopharmaceuticals. van de Weert, M. & Møller, E. H. (eds.). 1 ed. New York: Springer, p. 97-111

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  40. Published

    Preface

    van de Weert, Marco & Møller, E. H., 2008, Immunogenicity of biopharmaceuticals. van de Weert, M. & Møller, E. H. (eds.). 1 ed. New York: Springer, p. v-vi

    Research output: Chapter in Book/Report/Conference proceedingPreface/postscriptResearch

  41. Published

    Protein pharmaceuticals

    van de Weert, Marco & Møller, E. H., 2008, In: Drug Discovery Today: Technologies. 5, 2-3, p. 35-36

    Research output: Contribution to journalEditorialResearch

  42. Published
  43. Published

    Metabolism of [1,6-13C]glucose and [U-13C]glutamine and depolarization induced GABA release in superfused mouse cerebral cortical mini-slices

    Waagepetersen, Helle S., Døring, S. & Schousboe, Arne, 2008, In: Neurochemical Research. 33, 8, p. 1610-1617

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Characterization of 1,4-dideoxy-1,4-imino-d-arabinitol (DAB) as an inhibitor of brain glycogen shunt activity

    Walls, Anne Byriel, Sickmann, H. M., Brown, A., Bouman, S. D., Ransom, B., Schousboe, Arne & Waagepetersen, Helle S., 2008, In: Journal of Neurochemistry. 105, p. 1462-1470

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Characterization of GPRC6A: a 7TM receptor activated by L-alpha-amino acids and positively modulated by divalent cations

    Wellendorph, Petrine, Hansen, K. B., Christiansen, B., Burhenne, N., Balsgaard, A., Greenwood, J. R., Walter, B., Schmale, H., Egebjerg, J. & Bräuner, Hans, 2008, In: Fundamental and Clinical Pharmacology. Suppl. 2, p. 19

    Research output: Contribution to journalConference abstract in journalResearch

  46. Published

    Structure and molecular mechanism of a nucleobase-cation-symport-1 family transporter

    Weyand, S., Shimamura, T., Yajima, S., Suzuki, S., Mirza, Osman Asghar, Krusong, K., Carpenter, E. P., Rutherford, N. G., Hadden, J. M., O'Reilly, J., Ma, P., Saidijam, M., Patching, S. G., Hope, R. J., Norbertczak, H. T., Roach, P. C. J., Iwata, S., Henderson, P. J. F. & Cameron, A. D., 2008, In: Science. 322, 5902, p. 709-713

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Toward an understanding of the factors influencing anhydrate-to-hydrate transformation kinetics in aqueous environments

    Wikström, H., Rantanen, Jukka, Gift, A. D. & Taylor, L. S., 2008, In: Crystal Growth & Design. 8, 8, p. 2684-2693

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Green catalysts: Solid-phase peptide carbene ligands in aqueous transition metal catalysis

    Worm-Leonhard, K., 2008, København: Det Farmaceutiske Fakultet. 174 p.

    Research output: Book/ReportPh.D. thesisResearch

  49. Published

    First total synthesis of (+/-)-3-hydroxy-11-norcytisine: Structure confirmation and biological characterization

    Yohannes, D., Hansen, C. P., Akireddy, S. R., Hauser, T. A., Kiser, M. N., Gurnon, N. J., Day, C. S., Bhatti, B. & Caldwell, W. S., 2008, In: Organic Letters. 10, 23, p. 5353-5356

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    In vitro assay artefacts - an antiplasmodial perspective

    Ziegler, H. L., Staalsø, T., Hägerstrand, H. & Jaroszewski, J. W., 2008.

    Research output: Contribution to conferencePosterResearch

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