A comparative, BAC end sequence enabled map of the genome of the American mink (Neovison vison)
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A comparative, BAC end sequence enabled map of the genome of the American mink (Neovison vison). / Benkel, Bernhard F.; Smith, Amanda; Christensen, Knud; Anistoroaei, Razvan Marian; Zhang, Ye; Sensen, Christoph W.; Farid, Hossain; Paterson, Lyn; Teather, Ronald M.
In: Genes and Genomics, Vol. 34, No. 1, 2012, p. 83-91.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - A comparative, BAC end sequence enabled map of the genome of the American mink (Neovison vison)
AU - Benkel, Bernhard F.
AU - Smith, Amanda
AU - Christensen, Knud
AU - Anistoroaei, Razvan Marian
AU - Zhang, Ye
AU - Sensen, Christoph W.
AU - Farid, Hossain
AU - Paterson, Lyn
AU - Teather, Ronald M.
PY - 2012
Y1 - 2012
N2 - In this report we present the results of the analysis of approximately 2.7 Mb of genomic information for the American mink (Neovison vison) derived through BAC end sequencing. Our study, which encompasses approximately 1/1000th of the mink genome, suggests that simple sequence repeats (SSRs) are less common in the mink than in the human genome, whereas the average GC content of the mink genome is slightly higher than that of its human counterpart. The 2.7 Mb mink genomic dataset also contained 2,416 repeat elements (retroids and DNA transposons) occupying almost 31% of the sequence space. Among repeat elements, LINEs were over-represented and endogenous viruses (aka LTRs) under-represented in comparison to the human genome. Finally, we present a virtual map of the mink genome constructed with reference to the human and canine genome assemblies using a comparative genomics approach and incorporating over 200 mink BESs with unique hits to the human genome.
AB - In this report we present the results of the analysis of approximately 2.7 Mb of genomic information for the American mink (Neovison vison) derived through BAC end sequencing. Our study, which encompasses approximately 1/1000th of the mink genome, suggests that simple sequence repeats (SSRs) are less common in the mink than in the human genome, whereas the average GC content of the mink genome is slightly higher than that of its human counterpart. The 2.7 Mb mink genomic dataset also contained 2,416 repeat elements (retroids and DNA transposons) occupying almost 31% of the sequence space. Among repeat elements, LINEs were over-represented and endogenous viruses (aka LTRs) under-represented in comparison to the human genome. Finally, we present a virtual map of the mink genome constructed with reference to the human and canine genome assemblies using a comparative genomics approach and incorporating over 200 mink BESs with unique hits to the human genome.
KW - Former LIFE faculty
KW - American mink
KW - BAC end sequencing
KW - Comparatve mapping
KW - Structural genomics
U2 - 10.1007/s13258-011-0160-8
DO - 10.1007/s13258-011-0160-8
M3 - Journal article
VL - 34
SP - 83
EP - 91
JO - Genes and Genomics
JF - Genes and Genomics
SN - 1976-9571
IS - 1
ER -
ID: 37765863