Topoisomerase 1(TOP1) gene copy number in stage III colorectal cancer patients and its relation to prognosis

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

  • Maria Unni Koefoed Rømer
  • Sune Boris Nygård
  • Ib Jarle Christensen
  • Nielsen, Signe Lykke
  • Kirsten Vang Nielsen
  • Sven Müller
  • David Hersi Smith
  • Ben Vainer
  • Hans Jørgen Nielsen
  • Nils Brünner
A Topoisomerase 1 (Top1) poison is frequently included in the treatment regimens for metastatic colorectal cancer (mCRC). However, no predictive biomarkers for Top1 poisons are available. We here report a study on the TOP1 gene copy number in CRC patients and its association with patient prognosis and tumor cell proliferation.
OriginalsprogEngelsk
TidsskriftMolecular Oncology
Vol/bind7
Udgave nummer1
Sider (fra-til)101-111
Antal sider11
ISSN1574-7891
DOI
StatusUdgivet - 2013

    Forskningsområder

  • Det tidligere LIFE - Colorectal cancer, Prognosis, FISH, Topoisomerase 1, Gene copy number, Biomarker

ID: 40707423